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Naltrexone is an opioid antagonist that is best used as a part of a comprehensive addiction treatment program. It is designed for use during or after a successful detox. An opioid dependent individual will experience sudden opioid withdrawal if they take naltrexone.

It is generally advised that the person stop using any opioids for 7 to 10 days before taking naltrexone. In some cases, as many as 14 days may be required to fully detox from opioids. But to be safe, the best thing to do is follow your doctor’s prescription carefully. Side effects may occur while taking this drug. This includes nausea, vomiting, and cramping.

On this article we will be talking about how long naltrexone stays in a person’s system.

Do keep in mind that if someone uses opioids and naltrexone simultaneously, there is a chance that they’ll go into severe withdrawal, with extreme symptoms resembling an overdose. That is why it is important to know the half-life of naltrexone.

How Long Does Naltrexone Stay in Your System?

Despite its risks, naltrexone is a truly beneficial prescription medication. The average half-life of naltrexone is between 4 and 13 hours. With Vivitrol, the half-life is extended and it becomes much longer. The average half-life of the Vivitrol shot is between 5 to 19 days. This is because it is designed to be an extended-release drug. It is meant to stay in your system for a longer time.

What people don’t seem to realize is that the half-life doesn’t indicate the time it would take the entire dose of naltrexone to leave the system. It is actually a measure of how long it would take half of a dose of the drug to be processed and eliminated.

A drug like naltrexone can take several half-lives before being fully eliminated.

Factors That Change How Long Naltrexone Stays in Your System

Prescription medications may be affected by certain factors that change the way they are processed, and in turn, alters the time they remain in the body.

Age is one of them. As people get older, it takes much longer for the body to eliminate drugs from their system, especially compared to younger people. A patient’s overall health will affect this as well, because it dictates the body’s ability to process such medications.

If the person has any chronic illnesses, drugs may take longer to be removed from the system. And a person with a fast metabolism will process these drugs much like everything else they consume. Food? Energy? Fat? A quick metabolism processes these things quickly.

On the other hand, we can say that those with a slower metabolism will surely process drugs more slowly.

Your body mass and your hydration levels can also slow down or speed up this process.

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Hair, Urine, and Blood: How Long Does Naltrexone Stay?

This won’t be applicable to you unless your doctor decides to test you. There are certain instances wherein a person is tested by their doctor to make sure they are taking naltrexone as instructed.

Naltrexone can be detected in urine for about 4 to 6 hours if the patient takes the immediate-release version. A blood test can show most versions of oral naltrexone for up to 24 hours, the same goes with a saliva test.

In a hair follicle test, naltrexone can be present for up to 90 days.

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