In a recent study published in the journal Biological Psychiatry, scientists review the involvement of the gut microbiome in triggering the pathogenesis of mental disorders, including major depressive disorder and bipolar disorder.
The discovery of the gut microbiome-brain axis has revolutionized the field of psychiatry. Many case-control studies investigated the role of gut bacterial communities in altering human mental health.
Evidence suggests that the gut microbiome influences mental health conditions by modulating various biological processes, including the immune system and inflammation, mitochondrial dysfunction and oxidative stress, tryptophan-kynurenine metabolism, neuroendocrine metabolism, blood-brain barrier integrity, and neurotransmitter production.
In the current study, researchers discuss the contributions of comparatively lesser-explored gut microorganisms, such as viruses, fungi, archaea, and parasites, in influencing mood disorder pathophysiology.
A recent article on News-Medical explores the intriguing connection between gut health and mental well-being. Research has unveiled a fascinating correlation between the gut microbiome and its influence on mental health. The gut, often called the “second brain,” is home to trillions of microorganisms that play a pivotal role in maintaining overall health. This ecosystem of bacteria, fungi, and viruses appears to have a profound impact on our emotional and psychological states.
Studies suggest that an imbalance in the gut microbiome, known as dysbiosis, may contribute to mental health disorders such as anxiety, depression, and addiction. Researchers have discovered that the gut-brain axis, a communication highway between the gut and the brain, plays a vital role in regulating mood and behavior.
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