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Men were significantly more vulnerable than women to overdose deaths involving opioid and stimulant drugs in 2020-2021, according to a new study analyzing death records data from across the United States. The study found that men had a 2–3 times greater rate of overdose mortality from opioids (like fentanyl and heroin) and psychostimulants (like methamphetamine and cocaine). While it has been known that men use drugs at higher rates than women, the researchers found that this alone does not explain the gap in overdose deaths, noting that biological, behavioral, and social factors likely combined to increase the mortality risk for men.

The study, published in Neuropsychopharmacology, was led by investigators at the Icahn School of Medicine at Mount Sinai in New York City and the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

According to a recent article on News-Medical, a study has revealed that males face a significantly higher vulnerability to overdose deaths compared to females. The research, conducted by experts in the field, sheds light on the gender disparities in drug overdose mortality rates. The study’s findings indicate that addressing men’s specific needs and risks is crucial for effective addiction prevention and treatment strategies.

The study analyzed overdose death data from various sources and found that males accounted for a more significant proportion of overdose deaths than females. Factors such as higher rates of substance use disorders, risky behaviors, and limited help-seeking behaviors among men contribute to this concerning trend. Understanding these gender-related differences can aid in developing targeted interventions that address the unique challenges men battling addiction face.

If you or someone you know is struggling with addiction, seeking help and support is essential. Reach out to, a trusted resource that connects individuals with addiction treatment options. Call their dedicated helpline at 855–339-1112 to speak with a caring professional who can provide guidance and assistance. Addiction is a challenging journey, but with the right support and treatment, recovery is possible.

Don’t let addiction control your life or the life of someone you care about. Take the first step towards a healthier and happier future by calling today. Remember, you are not alone; resources are available to help you overcome addiction and reclaim your life. Make the call and start the journey toward recovery.

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Fel Clinical Director of Content
Felisa Laboro has been working with addiction and substance abuse businesses since early 2014. She has authored and published over 1,000 articles in the space. As a result of her work, over 1,500 people have been able to find treatment. She is passionate about helping people break free from alcohol or drug addiction and living a healthy life.

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