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How Long Can Fentanyl Stay In The Urine?

Before digging into the duration of Fentanyl in the urine, the elimination half-life of Fentanyl must first be looked into. Note that any form of Fentanyl including transdermal patches, transmucosal lozenges, and intravenous administration all have a varied half-life duration.

Fentanyl is an opioid analgesic first synthesized by Paul Janssen of Janssen Pharmaceutica. The primary aim for its formulation was to treat pain and pain disorders ranging from moderate to severe. It was later branded as an anesthetic in the 1960s with the name Sublimaze. Fentanyl is known to be a hundred times more potent than the drug morphine and up to 50 times more potent than the pharmaceutical drug heroine.

Intravenous Fentanyl

The drug has an elimination half-life of 2 to 4 hours. Most drugs, including Fentanyl, exhibit 5.5 half-lives. With this understanding, IV Fentanyl would then take as long as 11 to 22 hours for full elimination from the blood plasma.

Transdermal Patch Fentanyl

Another form of Fentanyl, the transdermal patch is believed to have a longer half-life elimination than the intravenous type as it clocks at approximately 13 to 22 hours. Thus, the complete process of elimination should take more than 2 to 5 days.

Transmucosal Lozenges Fentanyl

Transmucosal Lozenges have a shorter elimination half-life than the transdermal patch as it ranges from 5 to 15 hours. Therefore, the body will need 1.15 to 3.43 days to completely be cleared of this type of Fentanyl.

However, the aforementioned time frames may still vary with each patient. Likewise, time frames may be dependent on factors including but not limited to build, genetics, age, hydration levels, as well as, liver and kidney conditions. The prescribed dosage as well as what drugs could be co-administered may either aid or hinder the metabolism of this drug.

Fentanyl Side Effects

As one’s system adjusts to the drug in the course of treatment, a few notable side effects are expected to occur. Although several of these side effects do not necessitate medical attention, it is still necessary to know them to know the best time to call for professional help.

The most common known side effects of taking Fentanyl are:

  • Weight Loss
  • Irritability
  • Back Pain
  • Difficulty of movement
  • Diarrhea
  • Feelings of emptiness, sadness or discouragement
  • Joint Pain
  • Loss or Lack of Strength
  • Loss or Lack of Pleasure and Interest
  • Stiffness of Muscles
  • Unusual Tiredness
  • Unusual Drowsiness or Sleepiness
  • Trouble Concentrating
  • Trouble Sleeping


The Lesser Known Side Effects of Fentanyl use are:
  • Visual Changes
  • Feelings of Unstoppable Movement of Oneself or Surroundings
  • Feeling Extreme Warmth or Heat
  • Redness of the Skin, Neck, Face
  • Pain, Sores, Or Irritation On Application
  • Itchy Skin
  • Sweating
  • Muscle Tightness
  • Rash
  • Head Spinning sensation

Pass Fentanyl Out Of Your System

Be more physically active

Research reveals that higher amount of body fat may prolong Fentanyl elimination from the body. It has also been discovered that physical activity and regular exercise can reduce body fat, which can help in clearing the drug from the body.

Take Calcium-D-Glucarate

The cellular detoxifying agent has been known to help eliminate toxins from one’s kidneys and liver. Calcium D Glucarate can speed up the elimination of toxins from one’s body that is likely to come as a result of ingesting the drug.  RehabNearMe is dedicated to helping people live a life of sobriety and freedom.



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