In a recent study published in the journal Nutrients, researchers investigate the combined effects of caloric restriction (CR) and clinical psychological intervention (CPI) on the composition of the gut microbiome and stress-related mental health outcomes in women.
Common mental and metabolic disorders like obesity, depression, and diabetes share biological and lifestyle pathways, thus leading to their co-occurrence, as well as increased morbidity and mortality rates. Although pharmacological treatments exist to manage many of these disorders, adherence is challenging, and side effects like weight gain can reduce patient compliance, ultimately increasing the risk of adverse outcomes.